Preproteins couple the intrinsic dynamics of SecA to its ATPase cycle to translocate via a catch and release mechanism
S. Krishnamurthy, M. F. Sardis, N. Eleftheriadis, K. E. Chatzi, J. H. Smit, K. Karathanou, G. Gouridis, A. G. Portaliou, A.-N. Bondar, S. Karamanou, A. Economou
The paper reveals how SecA's intrinsic dynamics and preprotein interactions enable translocation via a catch and release mechanism.
bioRxiv · Aug 31, 2021Biochemistry