Author

S. L. Freedman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:simulation· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

A. R. Dinner· 2 shared S. Banerjee· 2 shared B. Xu· 1 shared C. Suarez· 1 shared D. R. Kovar· 1 shared D. S. Banerjee· 1 shared G. A. Voth· 1 shared G. M. Hocky· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiophysics

A. R. Dinner

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4 papers

Recent·Most cited

Growth-induced collective bending and kinetic trapping of cytoskeletal filaments

D. S. Banerjee, S. L. Freedman, M. P. Murrell, S. Banerjee

This study develops a model showing that rapid actin filament growth leads to kinetic trapping of bent filaments, influenced by subunit availability and crosslinking.

Cytoskeleton · May 22, 2024Peer-reviewedBiophysics

A dynamical systems treatment of transcriptomic trajectories in hematopoiesis

S. L. Freedman, B. Xu, S. Goyal, M. Mani

This paper applies a dynamical systems framework to transcriptomic data from hematopoiesis, identifying bifurcations in neutrophil differentiation and uncovering key gene contributors.

bioRxiv · May 3, 2021Biophysics

Mechanical and kinetic factors drive sorting of F-actin crosslinkers on bundles

S. L. Freedman, C. Suarez, J. D. Winkelman, D. R. Kovar, G. A. Voth, A. R. Dinner, G. M. Hocky

The paper investigates how mechanical and kinetic factors influence the sorting of F-actin crosslinkers on bundles, showing a non-monotonic dependence on polymerization rate.

bioRxiv · Dec 11, 2018Biophysics

Filament Rigidity And Connectivity Tune The Deformation Modes Of Active Biopolymer Networks

S. Stam, S. L. Freedman, S. Banerjee, K. L. Weirich, A. R. Dinner, M. L. Gardel

The paper shows how filament rigidity and connectivity in active biopolymer networks affect deformation modes, contractility, and anisotropy through experiments and simulations.

bioRxiv · May 25, 2017Biophysics