Author

S. L. Semple

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Assay:CUT&Tag· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. M. Soliman· 1 shared A. Nashiry· 1 shared D. R. Barreda· 1 shared D. Torrealba· 1 shared E. H. Albers· 1 shared F. Haddad· 1 shared K. B. Tierney· 1 shared K. L. Mossman· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. M. Soliman

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Author profile →

2 papers

Recent·Most cited

A cold-blooded vertebrate shows integration of antimicrobial defenses and tissue repair through fever

F. Haddad, A. M. Soliman, M. E. Wong, E. H. Albers, S. L. Semple, D. Torrealba, R. D. Heimroth, A. Nashiry, K. B. Tierney, D. R. Barreda

This study shows that fever in a cold-blooded fish integrates antimicrobial defenses and tissue repair by selectively activating immune mechanisms and inhibiting inflammation.

bioRxiv · Oct 27, 2022Immunology

Long dsRNA mediated RNA interference (dsRNAi) is antiviral in interferon competent mammalian cells

S. L. Semple, R. A. Jacob, K. L. Mossman, S. J. DeWitte-Orr

The paper shows that low-concentration dsRNA can inhibit viral replication in IFN-competent mammalian cells via RNAi, independent of IFN induction.

bioRxiv · Jan 14, 2022 · PreprintImmunology