A novel exosome biogenesis mechanism: multivesicular structures budding and rupturing at the plasma membrane
S. Leon Quinonez, I. R. Brown, H. E. Grimsley, J. Cinatl, M. Michaelis, C. Hsu
The paper identifies a novel exosome release mechanism where multivesicular structures protrude from the plasma membrane and rupture to release exosomes, distinct from the conventional multivesicular endosome fusion process.
bioRxiv · Nov 21, 2019 · PreprintCell Biology