Author

S. Lyon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A.-P. Foray· 1 shared B. Beutler· 1 shared C. H. Bu· 1 shared C. Marquet· 1 shared C. Pecquet· 1 shared C. Scazzocchio· 1 shared D. Xu· 1 shared E. M. Y. Moresco· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A.-P. Foray

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1 paper

Recent·Most cited

De novo germline mutation in the Dual Specificity Phosphatase 10 gene accelerates autoimmune diabetes in Non-Obese Diabetic (NOD) mice

A.-P. Foray, S. Candon, S. Hildebrand, C. Marquet, F. Valette, C. Pecquet, S. Lemoine, F. Langa-Vives, M. Dumas, P. Hu, P. Santamaria, S. Lyon, L. Scott, C. H. Bu, T. Wang, , L. Chatenoud

This study identifies a de novo germline mutation in Dusp10 that accelerates autoimmune diabetes in NOD mice by increasing susceptibility through CRISPR validation and PD-L1 expression analysis.

bioRxiv · Dec 30, 2020 · PreprintImmunology