Author

E. M. Y. Moresco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

B. Beutler· 2 shared S. Hildebrand· 2 shared A. Liu· 1 shared A.-P. Foray· 1 shared C. H. Bu· 1 shared C. Marquet· 1 shared C. Pecquet· 1 shared C. Scazzocchio· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

B. Beutler

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 30, 2020

De novo germline mutation in the Dual Specificity Phosphatase 10 gene accelerates autoimmune diabetes in Non-Obese Diabetic (NOD) mice

A.-P. Foray, S. Candon, S. Hildebrand…·L. Chatenoud

This study identifies a de novo germline mutation in Dusp10 that accelerates autoimmune diabetes in NOD mice by increasing susceptibility through CRISPR validation and PD-L1 expression analysis.

DOI 10.1101/2020.12.30.424747

mousewhole-genome sequencing

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 21, 2020

Mechanism of negative regulation of NF-κB by N4BP1

H. Shi, L. Sun, Y. Wang…·B. Beutler

This study identifies N4BP1 as an inhibitor of NF-κB activation by interacting with NEMO, and shows that caspase 8 cleavage inactivates N4BP1 during TRIF-dependent signaling.

DOI 10.1101/2020.10.21.349357

mouseexperimental assay

𝕏 PostBluesky