Novel quaternary structures of the human prion protein globular domain
L. Oliveira Bortot, V. Lopes Rangel, F. A. Pavlovici, K. El Omari, A. Wagner, J. Brandao-Neto, R. Talon, F. von Delft, A. G Reidenbach, S. M Vallabh, E. Vallabh Minikel, S. Schreiber, M. Cristina Nonato
This study reports a novel dimeric and oligomeric structure of human PrPC's globular domain and explores its structural dynamics and implications for prion conversion.
bioRxiv · Nov 16, 2020Biochemistry