Author

K. El Omari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein folding & dynamics· 3 Organism:human· 2 Assay:structural biology· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Wagner· 3 shared A. G Reidenbach· 1 shared C. A. Waudby· 1 shared C. J. Morris· 1 shared D. Guneri· 1 shared D. Pike· 1 shared E. Alexandrou· 1 shared E. Campbell· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBiochemistry

A. Wagner

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Author profile →

4 papers

Recent·Most cited

Structural Insights into Regulation of Insulin Expression Involving i-Motif DNA Structures in the Insulin-Linked Polymorphic Region.

D. Guneri, E. Alexandrou, K. El Omari, Z. Dvorakova, R. V. Chikhale, D. Pike, C. A. Waudby, C. J. Morris, S. Haider, G. N. Parkinson, Z. A. E. Waller

This study investigates how sequence variants in the insulin-linked polymorphic region form i-motif and G-quadruplex DNA structures, which regulate insulin gene expression.

bioRxiv · Jun 1, 2023 · PreprintBiophysics

Functional metagenomic screening in microfluidic droplets identifies a β-glucuronidase in an unprecedented sequence neighbourhood

S. Neun, P. Brear, E. Campbell, T. Tryfona, K. El Omari, A. Wagner, P. Dupree, M. Hyvonen, F. Hollfelder

This study identifies a novel β-glucuronidase from a metagenomic library using microfluidic droplet screening, revealing a new GH3 family member with unique functional and structural properties.

bioRxiv · Apr 25, 2022 · PreprintBiochemistry

Novel quaternary structures of the human prion protein globular domain

L. Oliveira Bortot, V. Lopes Rangel, F. A. Pavlovici, K. El Omari, A. Wagner, J. Brandao-Neto, R. Talon, F. von Delft, A. G Reidenbach, S. M Vallabh, E. Vallabh Minikel, S. Schreiber, M. Cristina Nonato

This study reports a novel dimeric and oligomeric structure of human PrPC's globular domain and explores its structural dynamics and implications for prion conversion.

bioRxiv · Nov 16, 2020Biochemistry

Identifying dynamic, partially occupied residues using anomalous scattering

S. Rocchio, R. Duman, K. El Omari, V. Mykhaylyk, Z. Yan, A. Wagner, J. C. A. Bardwell, S. Horowitz

This study presents methods to detect dynamic, partially occupied protein conformations in crystals using anomalous scattering signals with low occupancy.

bioRxiv · May 20, 2019Biophysics