Author

S. M. Belcher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 3 Assay:proteomics· 3 Research Focus:ecology & biodiversity· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

T. W. Jackson· 4 shared E. S. Baker· 2 shared M. E. Polera· 2 shared A. K. Boatman· 1 shared C. C. Burton· 1 shared C. J. Cookman· 1 shared C. M. Scheibly· 1 shared D. M. Reif· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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4 shared papersPharmacology & Toxicology

T. W. Jackson

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7 papers

Recent·Most cited

Quantitative Cross-Species Comparison of Serum Albumin Binding of Per- and Polyfluoroalkyl Substances from Five Structural Classes

H. M. Starnes, T. W. Jackson, K. D. Rock, S. M. Belcher

The paper compares serum albumin binding of PFAS congeners across human, bovine, porcine, and rat species using differential scanning fluorimetry, finding interspecies differences in binding affinities.

bioRxiv · Nov 10, 2023Pharmacology & Toxicology

Assessing Per- and Polyfluoroalkyl Substances (PFAS) in Fish Fillet Using Non-Targeted Analyses

A. K. Boatman, J. R. Chappel, M. E. Polera, J. N. Dodds, S. M. Belcher, E. S. Baker

The paper assesses PFAS in fish fillets from North Carolina using non-targeted analyses, detecting 36 PFAS including 19 not found by routine methods and high PFOS levels.

bioRxiv · Sep 1, 2023Pharmacology & Toxicology

Blood Concentrations of Per- and Polyfluoroalkyl Substances are Associated with Autoimmunity-like Effects in the American Alligator

T. Guillette, T. W. Jackson, M. Guillette, J. MCCord, S. M. Belcher

This study finds elevated PFAS levels in American alligators from the Cape Fear River are linked to immune dysfunction and autoimmune-like effects.

bioRxiv · Feb 15, 2022 · PreprintPharmacology & Toxicology

Gestational Cd Exposure in the CD-1 Mouse Sex-Specifically Disrupts Essential Metal Ion Homeostasis

T. W. Jackson, O. Baars, S. M. Belcher

This study shows gestational cadmium exposure in CD-1 mice sex-specifically disrupts metal ion homeostasis, leading to metabolic issues in females.

bioRxiv · Nov 6, 2021Pharmacology & Toxicology

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances

K. I. Kirkwood, J. Fleming, H. Nguyen, D. M. Reif, E. S. Baker, S. M. Belcher

This study uses pine needles and a non-targeted method to detect over 70 PFAS across six decades, revealing temporal and spatial patterns of exposure and contamination.

bioRxiv · Aug 24, 2021Pharmacology & Toxicology

Rapid Characterization of Human Serum Albumin Binding for Per- And Polyfluoroalkyl Substances Using Differential Scanning Fluorimetry

T. W. Jackson, C. M. Scheibly, M. E. Polera, S. M. Belcher

This study develops a differential scanning fluorimetry assay to rapidly determine albumin binding affinities for various PFAS compounds.

bioRxiv · Jun 13, 2021Pharmacology & Toxicology

Estrogen and Soy Isoflavonoids Decrease Sensitivity of Medulloblastoma and Central Nervous System Primitive Neuroectodermal Tumor Cells to Chemotherapeutic Cytotoxicity

S. M. Belcher, C. C. Burton, C. J. Cookman, M. Kirby, G. L. L. Miranda, F. Saeed, K. E. Wray

This study shows that estrogen and soy isoflavonoids reduce the sensitivity of medulloblastoma cells to chemotherapeutic drugs by protecting them from cytotoxicity.

BMC Pharmacology and Toxicology · Sep 6, 2017Peer-reviewedPharmacology & Toxicology