Author

S. M. Bruggink

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Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

B. J. Renquist· 2 shared J. M. Kronenfeld· 2 shared C. E. Geisler· 1 shared F. A. Duca· 1 shared J. Yoshino· 1 shared K. E. Miller· 1 shared K. P. Kentch· 1 shared S. Ghimire· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersPhysiology

B. J. Renquist

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2 papers

Recent·Most cited

A Leak-Free Head-Out Plethysmography System to Accurately Assess Lung Function in Mice

S. M. Bruggink, K. P. Kentch, J. M. Kronenfeld, B. J. Renquist

This paper develops a leak-free head-out plethysmography system for accurate, non-terminal lung function measurements in mice and validates its performance using various physiological parameters.

bioRxiv · Dec 1, 2021 · PreprintPhysiology

A Critical Role of Hepatic GABA in The Metabolic Dysfunction and Hyperphagia of Obesity

C. E. Geisler, S. Ghimire, S. M. Bruggink, K. E. Miller, S. N. Weninger, J. M. Kronenfeld, J. Yoshino, S. Klein, F. A. Duca, B. J. Renquist

This study shows that inhibiting hepatic GABA production in obese mice reduces hyperinsulinemia, improves glucose tolerance, and decreases food intake, suggesting a role for hepatic GABA in obesity-related metabolic dysfunction.

bioRxiv · Apr 2, 2020Physiology