iRGD-liposomes enhance tumor delivery and therapeutic efficacy of antisense oligonucleotide drugs against primary prostate cancer and bone metastasis
J. Guan, H. Guo, T. Tang, Y. Wang, Y. Wei, P. Seth, Y. Li, S. M. Dehm, E. Ruoslahti, H.-B. Pang
This paper demonstrates that iRGD-liposomes enhance the delivery and efficacy of AR-ASO in treating prostate cancer and bone metastasis without increasing toxicity.
bioRxiv · Jan 8, 2021Cancer Biology