Author

S. M. Lichtinger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:deep learning· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Garaizar· 1 shared A. Reinhardt· 1 shared J. L. Parker· 1 shared P. Biggin· 1 shared P. C. Biggin· 1 shared R. Collepardo-Guevara· 1 shared S. Newstead· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

A. Garaizar

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3 papers

Recent·Most cited

The mechanism of mammalian proton-coupled peptide transporters

S. M. Lichtinger, J. L. Parker, S. Newstead, P. Biggin

This study uses molecular dynamics simulations to elucidate the conformational mechanism and proton-substrate coupling in mammalian POTs, revealing key structural differences and functional insights.

bioRxiv · Feb 4, 2024Biophysics

Tackling hysteresis in conformational sampling - how to be forgetful with MEMENTO

S. M. Lichtinger, P. C. Biggin

This paper introduces MEMENTO, a method to generate conformational transition paths in proteins that reduces hysteresis in molecular dynamics simulations, outperforming traditional targeted MD approaches.

bioRxiv · Jan 28, 2023Biophysics

Targeted modulation of protein liquid-liquid phase separation by evolution of amino-acid sequence

S. M. Lichtinger, A. Garaizar, R. Collepardo-Guevara, A. Reinhardt

This paper evolves amino-acid sequences to modulate liquid-liquid phase separation in proteins, finding that sequence changes and environmental factors influence phase-separation behavior.

bioRxiv · Oct 20, 2020Biophysics