Author

A. Reinhardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Approach:statistical model· 3 Research Focus:protein folding & dynamics· 2 Assay:protein sequence· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

R. Collepardo-Guevara· 3 shared J. A. Joseph· 2 shared P. Y. Chew· 2 shared A. Anandamurugan· 1 shared A. Garaizar· 1 shared A. V. Artemov· 1 shared C. Gustafsson· 1 shared C. Lan· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersBiophysics

R. Collepardo-Guevara

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Author profile →

5 papers

Recent·Most cited

Aromatic and arginine content drives multiphasic condensation of protein-RNA mixtures

P. Y. Chew, J. A. Joseph, R. Collepardo-Guevara, A. Reinhardt

This study uses simulations to show that aromatic and arginine residues drive multiphasic condensation of protein-RNA mixtures, enabling design of synthetic condensates.

bioRxiv · Apr 5, 2023Biophysics

Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior to condensation

C. Lan, J. Kim, S. Ulferts, F. Aprile-Garcia, A. Anandamurugan, R. Grosse, R. Sawarkar, A. Reinhardt, T. Hugel

The paper uses fluorescence microscopy to study protein clusters before condensation, finding dynamic clusters that are not freely diffusing and exist even in unstressed cells.

bioRxiv · Aug 1, 2022Biophysics

Designing multiphase biomolecular condensates by coevolution of protein mixtures

P. Y. Chew, J. A. Joseph, R. Collepardo-Guevara, A. Reinhardt

This study designs protein pairs that form multiphase biomolecular condensates using a computational method combining genetic algorithms and coarse-grained models.

bioRxiv · Apr 22, 2022Biophysics

Cell-intrinsic functions of the transcription factor Bhlhe40 in activated B cells and T follicular helper cells restrain the germinal center reaction and prevent lymphomagenesis

R. Rauschmeier, A. Reinhardt, C. Gustafsson, V. Glaros, A. V. Artemov, R. Taneja, R. Mansson, M. Busslinger, T. Kreslavsky

This study shows that Bhlhe40 restrains germinal center reaction in B and T cells, preventing lymphoma by limiting TFH and GC B cell proliferation.

bioRxiv · Mar 12, 2021Immunology

Targeted modulation of protein liquid-liquid phase separation by evolution of amino-acid sequence

S. M. Lichtinger, A. Garaizar, R. Collepardo-Guevara, A. Reinhardt

This paper evolves amino-acid sequences to modulate liquid-liquid phase separation in proteins, finding that sequence changes and environmental factors influence phase-separation behavior.

bioRxiv · Oct 20, 2020Biophysics