Author

S. M. McCauley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Luban· 3 shared A. Dauphin· 2 shared C. Carbone· 2 shared K. Kim· 2 shared W. E. Diehl· 2 shared A. Nowosielska· 1 shared C. Strambio-De-Castillia· 1 shared E. M. Campbell· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMicrobiology

J. Luban

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Author profile →

3 papers

Recent·Most cited

IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus

M. H. Guney, K. Nagalekshmi, S. M. McCauley, C. Carbone, O. Aydemir, J. Luban

This study identifies IFIH1 (MDA5) as essential for innate immune detection of intron-containing RNA from the HIV-1 provirus, linking it to chronic inflammation in HIV-1 patients.

bioRxiv · Nov 17, 2023 · PreprintMicrobiology

Cyclophilin A protects HIV-1 from restriction by human TRIM5α

K. Kim, A. Dauphin, S. Komurlu, L. Yurkovetskiy, W. E. Diehl, S. M. McCauley, C. Carbone, C. Strambio-De-Castillia, E. M. Campbell, J. Luban

This study shows that Cyclophilin A protects HIV-1 from restriction by human TRIM5α by shielding the viral capsid from early inhibition during infection.

bioRxiv · Aug 24, 2019Microbiology

Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines

S. M. McCauley, K. Kim, A. Nowosielska, A. Dauphin, W. E. Diehl, J. Luban

The paper shows that HIV-1 provirus RNA activates innate immune responses through post-transcriptional elements, suggesting new therapeutic targets.

bioRxiv · Apr 5, 2018Microbiology