S. M. Parkhurst

Calcium influx rapidly establishes distinct spatial recruitments of Annexins to cell wounds

The paper shows that calcium influx quantity, not phospholipid binding, determines distinct Annexin recruitment patterns to cell wounds in Drosophila, which is critical for actomyosin ring formation and wound closure.

Two Septin Complexes Mediate Actin Dynamics During Cell Wound Repair

This study identifies two distinct Septin complexes that regulate actin dynamics during cell wound repair in Drosophila.

The Centralspindlin proteins Pavarotti and Tumbleweed work with WASH to regulate Nuclear Envelope budding

This study identifies Pavarotti and Tumbleweed as new components of the nuclear envelope budding machinery that work with WASH to regulate structural aspects of NE budding.

Cell wound repair requires the coordinated action of linear and branched actin nucleation factors

This study shows that branched actin nucleators scaffold the contractile actomyosin cable during wound repair, and their removal leads to alternative mechanisms of wound closure through linear actin filaments.

Wash and the WASH Regulatory Complex function in Nuclear Envelope budding

The paper identifies Wash and its regulatory complex as novel players in nuclear envelope budding, revealing a bipotent role for Wash and its impact on Lamin A/B meshworks.

The kinesin-like protein Pavarotti functions non-canonically to regulate actin dynamics

This study shows that Pavarotti, a Drosophila kinesin-like protein, binds directly to actin and regulates actin dynamics independently of Tumbleweed during wound repair and oogenesis.