Bcr-Abl tyrosine kinase inhibitor imatinib as a potential drug for COVID-19
N. S. Mulgaonkar, H. Wang, S. Mallawarachchi, D. Ruzek, B. Martina, S. Fernando
This paper reports that imatinib, an FDA-approved Bcr-Abl inhibitor, inhibits SARS-CoV-2 and other coronaviruses by blocking viral membrane fusion, suggesting its potential as a repurposed drug for COVID-19.
bioRxiv · Jun 18, 2020Microbiology