MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation
R. Pantier, M. Brown, S. Han, K. Paton, S. Meek, T. Montavon, T. McHugh, D. A. Kelly, T. Hochepied, C. Libert, T. Jenuwein, T. Burdon, A. Bird
This paper shows MeCP2 binds methylated DNA without needing phase separation or heterochromatin, and its foci are rare in most mammals.
bioRxiv · May 9, 2023Cell Biology