Author

S. Michalakis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Hess· 1 shared D. M. Mittas· 1 shared D. Otify· 1 shared E. Becirovic· 1 shared F. R. Traube· 1 shared G. Giorgio· 1 shared J. Wijnholds· 1 shared K. S. Hinrichsmeyer· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. J. Hess

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The type of DNA damage response after Decitabine treatment depends on the level of DNMT activity

T. Aumer, L. Bergmayr, S. Kartika, T. Zeng, Q. Ge, G. Giorgio, M. Daether, A. J. Hess, S. Michalakis, F. R. Traube

This study shows that Decitabine's DNA damage response depends on DNMT activity levels, with different repair pathways activated under varying conditions.

bioRxiv · Sep 2, 2023Biochemistry

mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy

L. M. Riedmayr, K. S. Hinrichsmeyer, S. B. Thalhammer, N. Karguth, S. Boehm, D. M. Mittas, V. J. Weber, D. Otify, V. Splith, M. Bruemmer, N. Boon, J. Wijnholds, V. Mehlfeld, S. Michalakis, S. Fenske, , E. Becirovic

This paper introduces REVeRT, a dual AAV vector system using mRNA trans-splicing for efficient gene delivery and editing, showing improved reconstitution and therapeutic potential in a mouse model.

bioRxiv · Feb 7, 2023Bioengineering