Author

F. R. Traube

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

T. Carell· 2 shared A. J. Hess· 1 shared A. R. Ofial· 1 shared C. B. Mulholland· 1 shared C. C. Sommermann· 1 shared E. Parsa· 1 shared E.-M. Eckl· 1 shared G. Giorgio· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

T. Carell

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Author profile →

3 papers

Recent·Most cited

The type of DNA damage response after Decitabine treatment depends on the level of DNMT activity

T. Aumer, L. Bergmayr, S. Kartika, T. Zeng, Q. Ge, G. Giorgio, M. Daether, A. J. Hess, S. Michalakis, F. R. Traube

This study shows that Decitabine's DNA damage response depends on DNMT activity levels, with different repair pathways activated under varying conditions.

bioRxiv · Sep 2, 2023Biochemistry

Epigenetic anti-cancer treatment with a stabilized carbocyclic Decitabine analogue

F. R. Traube, N. F. Bras, W. P. Roos, C. C. Sommermann, T. Diehl, R. J. Mayer, A. R. Ofial, M. Müller, H. Zipse, T. Carell

This paper evaluates a stabilized carbocyclic Decitabine analogue, showing it effectively inhibits DNMT1 and induces more DNA damage in cancer cells with less toxicity.

bioRxiv · Jan 19, 2022Cancer Biology

Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency

C. B. Mulholland, F. R. Traube, E. Parsa, E.-M. Eckl, M. Schoenung, M. Modic, M. D. Bartoschek, P. Stolz, J. Ryan, T. Carell, H. Leonhardt, S. Bultmann

The paper compares TET1 and TET2 contributions to cytosine oxidation during naive to primed pluripotency transition, finding distinct and differentiation-dependent roles in 5hmC and 5fC formation.

bioRxiv · Mar 13, 2018Cell Biology