Author

S. Miethe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

M. S. Denzel· 2 shared S. Ruegenberg· 2 shared U. Baumann· 2 shared B. Schermer· 1 shared C. Beisswenger· 1 shared C. Herr· 1 shared F. A. M. C. Mayr· 1 shared F. Ritzmann· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

M. S. Denzel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mutual regulation of transcriptomes between pneumocytes and fibroblasts mediates alveolar regeneration

Y. Yao, S. Miethe, K. Kattler, J. Walter, N. Schneider-Daum, C. Herr, H. Garn, F. Ritzmann, R. Bals, C. Beisswenger

The paper shows that co-culturing fibroblasts with pneumocytes enhances epithelial markers and barrier function, while fibroblasts upregulate IL-6 and other factors, suggesting mutual regulation in alveolar regeneration.

bioRxiv · Feb 27, 2023 · PreprintCell Biology

GFAT2 and AMDHD2 act in tandem to control the hexosamine biosynthetic pathway

V. Kroef, S. Ruegenberg, M. Horn, K. Allmeroth, L. Eberg, S. Bozkus, S. Miethe, B. Schermer, U. Baumann, M. S. Denzel

This study identifies AMDHD2 as a new regulator of the hexosamine biosynthetic pathway, showing it balances GFAT2 activity to control UDP-GlcNAc levels in mouse embryonic stem cells.

eLife · Mar 1, 2022Peer-reviewedBiochemistry

Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1

S. Ruegenberg, F. A. M. C. Mayr, S. Miethe, I. Atanassov, U. Baumann, M. S. Denzel

This study identifies how PKA phosphorylation of GFAT-1 modulates the hexosamine pathway by altering feedback inhibition and enzyme activity.

bioRxiv · Jul 23, 2020Biochemistry