Author

M. S. Denzel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. Allmeroth· 3 shared S. Miethe· 2 shared S. Ruegenberg· 2 shared U. Baumann· 2 shared A. Annibal· 1 shared A. Antebi· 1 shared A. Mesaros· 1 shared A. Pouikli· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBiochemistry

K. Allmeroth

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GFAT2 and AMDHD2 act in tandem to control the hexosamine biosynthetic pathway

V. Kroef, S. Ruegenberg, M. Horn, K. Allmeroth, L. Eberg, S. Bozkus, S. Miethe, B. Schermer, U. Baumann, M. S. Denzel

This study identifies AMDHD2 as a new regulator of the hexosamine biosynthetic pathway, showing it balances GFAT2 activity to control UDP-GlcNAc levels in mouse embryonic stem cells.

eLife · Mar 1, 2022Peer-reviewedBiochemistry

Hexosamine pathway activation improves memory but does not extend lifespan in mice.

K. Allmeroth, M. D. Hartman, M. Purrio, A. Mesaros, M. S. Denzel

This study examines the effects of hexosamine pathway activation in mice through dietary supplementation and genetic manipulation, finding improved memory but no lifespan extension.

bioRxiv · Jan 7, 2022Physiology

Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1

S. Ruegenberg, F. A. M. C. Mayr, S. Miethe, I. Atanassov, U. Baumann, M. S. Denzel

This study identifies how PKA phosphorylation of GFAT-1 modulates the hexosamine pathway by altering feedback inhibition and enzyme activity.

bioRxiv · Jul 23, 2020Biochemistry

Polyamine-controlled proliferation and protein biosynthesis are independent determinants of hair follicle stem cell fate

K. Allmeroth, C. S. Kim, A. Annibal, A. Pouikli, C. A. Chacon-Martinez, C. Latza, A. Antebi, P. Tessarz, S. A. Wickström, M. S. Denzel

This study shows polyamines regulate hair follicle stem cell fate through translation rates and N1-acetylspermidine, which increases proliferation without reducing translation.

bioRxiv · Apr 30, 2020 · PreprintCell Biology