Author

S. Montserrat-Sangra

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Kurimchak· 1 shared C. Herrera-Montavez· 1 shared D. Araiza-Olivera· 1 shared J. Hu· 1 shared J. Jin· 1 shared J. S. Duncan· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

A. M. Kurimchak

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1 paper

Recent·Most cited

Cancer BiologybioRxivDec 2, 2021

MDR1 Drug Efflux Pump Promotes Intrinsic and Acquired Resistance to PROTACs in Cancer Cells

A. M. Kurimchak, C. Herrera-Montavez, S. Montserrat-Sangra…·J. S. Duncan

This study identifies MDR1 as a mediator of resistance to PROTACs in cancer cells and shows that combining MDR1 inhibitors with PROTACs enhances drug efficacy.

DOI 10.1126/scisignal.abn2707

humanproteomics

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