Fitness costs of pfhrp2 and pfhrp3 deletions underlying diagnostic evasion in malaria parasites
S. Nair, X. Li, S. Nkhoma, T. J. Anderson
The paper measures fitness costs of pfhrp2 and pfhrp3 deletions in malaria parasites using CRISPR/Cas9 and competition experiments, finding costs consistent with diagnostic selection driving their spread in some regions.
bioRxiv · Feb 11, 2022Microbiology