Proteasome-Bound UCH37 Debranches Ubiquitin Chains to Promote Degradation
K. K. Deol, S. O. Crowe, J. Du, H. A. Bisbee, R. G. Guenette, E. R. Strieter
This study identifies UCH37 as a debranching deubiquitinase that promotes proteasomal degradation by cleaving K48 branched ubiquitin chains.
bioRxiv · Feb 21, 2020Biochemistry