In vitro model for resistance in oncogene-dependent tumors at the limit of radiological detectability
N. Müller, J. Brägelmann, C. Lorenz, U. P. Michel, D. Plenker, S. Ortiz-Cuaran, J. Weiss, R. Büttner, M. Peifer, R. K. Thomas, M. L. Sos, J. Berg
The paper develops an in vitro model to study resistance mechanisms in oncogene-dependent tumors and shows that combining drugs targeting multiple resistance pathways can inhibit resistant and drug-tolerant cell growth.
bioRxiv · Sep 5, 2019 · PreprintCancer Biology