Author

D. Plenker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. A. Tuveson· 2 shared A. Rishi· 1 shared A. Singhi· 1 shared A. Zureikat· 1 shared B. Haab· 1 shared B. Staal· 1 shared C. Bautista· 1 shared C. Fan· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

D. A. Tuveson

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Author profile →

4 papers

Recent·Most cited

Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristics

S. Bhatia, M. Kramer, S. Russo, P. Naik, G. Arun, K. Brophy, P. A. Andrews, C. Fan, C. M. Perou, J. Preall, T. Ha, D. Plenker, D. Tuveson, A. Rishi, J. E. Wilkinson, , D. L. Spector

This study develops and characterizes patient-derived TNBC organoids that recapitulate tumor properties and identify key signaling pathways involved in cancer progression.

bioRxiv · Aug 9, 2021Cancer Biology

DETECTION OF INCIPIENT PANCREATIC CANCER WITH NOVEL TUMOR-SPECIFIC ANTIBODIES IN MOUSE MODELS

T. E. Oni, C. Bautista, J. R. Merrill, J. A. C. M. Goos, K. D. Rivera, K. Miyabayashi, G. Biffi, L. Garcia, D. Plenker, H. Patel, E. Elyada, M. Samaritano, K. H. Yu, D. J. Pappin, M. G. Goggins, , D. A. Tuveson

This study develops tumor-specific antibodies for early detection of pancreatic cancer using PET imaging in mouse models, identifying two mAbs that bind to CEACAM6 variants in tumors.

bioRxiv · Sep 10, 2020 · PreprintCancer Biology

Detection of Chemotherapy-Resistant Pancreatic Cancer Using a Glycan Biomarker

C. Gao, L. Wisniewski, Y. Liu, B. Staal, I. Beddows, D. Plenker, M. Aldakkak, J. Hall, D. Barnett, M. Kheir Gouda, P. Allen, R. Drake, A. Zureikat, Y. Huang, D. Evans, , B. Haab

This paper identifies sTRA as a glycan biomarker for chemotherapy-resistant pancreatic cancer, showing its presence correlates with poor treatment response in multiple systems.

bioRxiv · Jun 1, 2020 · PreprintCancer Biology

In vitro model for resistance in oncogene-dependent tumors at the limit of radiological detectability

N. Müller, J. Brägelmann, C. Lorenz, U. P. Michel, D. Plenker, S. Ortiz-Cuaran, J. Weiss, R. Büttner, M. Peifer, R. K. Thomas, M. L. Sos, J. Berg

The paper develops an in vitro model to study resistance mechanisms in oncogene-dependent tumors and shows that combining drugs targeting multiple resistance pathways can inhibit resistant and drug-tolerant cell growth.

bioRxiv · Sep 5, 2019 · PreprintCancer Biology