S. P. Becerra

PEDF and Derived Peptides Prevent Apoptosis and Promote Differentiation of Retinal Photoreceptors

This study shows that PEDF and its neurotrophic peptides protect retinal photoreceptors from apoptosis and promote differentiation, while peptides from the antiangiogenic region have no effect.

Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-derived Factor Receptor (PEDF-R)

This study shows that PEDF-R is essential for efficient degradation of photoreceptor outer segments by RPE cells, as its absence impairs lipid metabolism and rhodopsin breakdown during phagocytosis.