Discovery of another mechanism for the inhibition of particulate guanylyl cyclases by the natriuretic peptide clearance receptor
D. Liu, R. P. Ceddia, W. Zhang, F. Shi, H. Fang, S. P. Collins
This paper identifies a new mechanism by which NPRC inhibits NP signaling by forming heterodimers with NPRA or NPRB, preventing cGMP production.
bioRxiv · Sep 6, 2022Biochemistry