Author

S. P. Demas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

K. A. Henzler-Wildman· 2 shared A. K. Wegrzynowicz· 1 shared A. Wegrzynowicz· 1 shared C. J. Porter· 1 shared E. N. Powers· 1 shared J. M. Peters· 1 shared M. S. McLean· 1 shared P. J. Spreacker· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

K. A. Henzler-Wildman

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2 papers

Recent·Most cited

A Small Multidrug Resistance Transporter in Pseudomonas aeruginosa Confers Substrate-Specific Resistance or Susceptibility

A. K. Wegrzynowicz, W. J. Heelan, S. P. Demas, M. S. McLean, J. M. Peters, K. A. Henzler-Wildman

This paper investigates PAsmr, an SMR transporter in P. aeruginosa, showing it can confer both resistance and susceptibility to antimicrobial compounds through proton leak mechanisms.

bioRxiv · Sep 28, 2023 · PreprintBiochemistry

Functional promiscuity of small multidrug resistance transporters from Staphylococcus aureus, Pseudomonas aeruginosa, and Francisella tularensis

P. J. Spreacker, C. J. Porter, A. Wegrzynowicz, W. F. Beeninga, S. P. Demas, E. N. Powers, K. A. Henzler-Wildman

The paper tests whether functional promiscuity of SMR transporters extends to homologs from three pathogens, finding they can confer resistance or susceptibility to different substrates in E. coli.

bioRxiv · Nov 22, 2022 · PreprintMicrobiology