S. Peng

The paper identifies a novel glymphatic pathway in the optic nerve for clearing amyloid-beta from the vitreous, which is impaired in glaucoma.

This study shows that JAM-A deficiency in female mice increases microglia activation and GBM growth, revealing a sex-specific role for JAM-A in the tumor microenvironment.

The paper uses proximity proteomics to map the apical-lateral border in MDCK-II cells, identifying a new membrane compartment defined by Pals1.

MATE-Seq identifies antigen-specific T-cell receptors by isolating and sequencing T-cells bound to peptide-MHC tetramers with high sensitivity.

This study identifies reduced diffusional conductance to CO2 as the main factor limiting photosynthesis in salt-stressed rice leaves.

This study uses single molecule FRET to show Cas9 undergoes conformational changes and long-range allosteric communication that regulate DNA cleavage, identifying key residues for improving CRISPR/Cas9 specificity.