Author

A. M. Xu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bhargava· 1 shared A. Gamboa· 1 shared A. H. Ng· 1 shared A. Jiang· 1 shared A. Merchant· 1 shared A. R. Colombo· 1 shared A. S. Farooq· 1 shared C. Steidl· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Bhargava

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Author profile →

3 papers

Recent·Most cited

Identifying perturbations that boost T-cell infiltration into tumours via counterfactual learning of their spatial proteomic profiles

Z. J. Wang, A. S. Farooq, Y.-J. Chen, A. Bhargava, A. M. Xu, M. Thomson

The paper develops a deep-learning model to identify minimal tumour perturbations that enhance T-cell infiltration using spatial proteomic data from cancer samples.

bioRxiv · Oct 12, 2023Cancer Biology

Single cell spatial analysis and biomarker discovery in Hodgkin lymphoma

A. M. Xu, A. Jiang, T. Aoki, A. Gamboa, L. Chong, A. R. Colombo, Y. Yin, J. Lownik, K. Takata, M. Hav, C. Steidl, A. Merchant

This study uses spatial imaging to analyze Hodgkin lymphoma tumor microenvironments and identifies new biomarkers related to immune cell interactions and checkpoints.

bioRxiv · May 24, 2023 · PreprintCancer Biology

MATE-Seq: Microfluidic Antigen-TCR Engagement Sequencing

A. H. Ng, S. Peng, A. M. Xu, W. J. Noh, K. Guo, M. T. Bethune, W. Chour, J. Choi, S. Yang, D. Baltimore, J. R. Heath

MATE-Seq identifies antigen-specific T-cell receptors by isolating and sequencing T-cells bound to peptide-MHC tetramers with high sensitivity.

bioRxiv · Jul 18, 2019Immunology