Multivalent proteins rapidly and reversibly phase-separate upon osmotic cell volume change
A. P. Jalihal, S. Pitchiaya, L. Xiao, P. Bawa, X. Jiang, K. Bedi, A. Parolia, M. Cieslik, M. Ljungman, A. M. Chinnaiyan, N. G. Walter
The paper shows multivalent proteins rapidly phase-separate during hyperosmotic stress and reversibly dissolve upon osmotic rescue, impacting transcription termination.
Molecular Cell · Sep 1, 2020Peer-reviewedCell Biology