Partial loss of colonic primary cilia promotes inflammation and carcinogenesis
R. Tang, C. Paul, R. Lattanzio, T. Eguether, H. Tulari, J. Bremond, C. Maurizy, S. Poupeau, A. Turtoi, M. Svrcek, P. Seksik, V. Castronovo, P. Delvenne, B. Lemmers, C. Janke, , M. Hahne
This study shows that reduced colonic primary cilia in fibroblasts promotes inflammation and cancer in mouse models and human disease.
bioRxiv · Dec 20, 2019 · PreprintCancer Biology