Mechanisms of antibody binding revealed by asymmetric Fab-virus complexes
D. J. Goetschius, S. R. Hartmann, L. J. Organtini, H. Callaway, K. Huang, C. M. Bator, R. E. Ashley, A. M. Makhov, J. F. Conway, C. R. Parrish, S. L. Hafenstein
The paper uses cryo-EM to analyze antibody binding to parvovirus capsids, revealing structural insights into epitope-receptor interactions and species-specific neutralization.
bioRxiv · Dec 1, 2020 · PreprintMicrobiology