C. R. Parrish

Viral capsid, antibody, and receptor interactions: experimental analysis of the antibody escape evolution of canine parvovirus

This study uses in vitro selection and deep sequencing to identify escape mutations in canine parvovirus selected by two antibodies, revealing mechanisms of antibody and receptor binding interactions.

Understanding the Divergent Evolution and Epidemiology of H3N8 Influenza Viruses in Dogs and Horses

This paper compares the evolution and epidemiology of H3N8 influenza viruses in dogs and horses to understand their distinct evolutionary fates and potential zoonotic risks.

Parvovirus infection affects host cell nucleolar organization and ribosome biogenesis

This study investigates how canine parvovirus infection alters nucleolar structure and ribosome biogenesis using advanced imaging and biochemical techniques.

Mechanisms of antibody binding revealed by asymmetric Fab-virus complexes

The paper uses cryo-EM to analyze antibody binding to parvovirus capsids, revealing structural insights into epitope-receptor interactions and species-specific neutralization.

Influenza A viruses serially passaged in different MDCK cell lines exhibit limited sequence variation across their genomes, with the exception of the hemagglutinin gene

This study passaged influenza A viruses in different MDCK cell lines and found limited genome-wide sequence variation, with most mutations occurring in the hemagglutinin gene.

The effects of modified sialic acids on mucus and erythrocytes on influenza A virus HA and NA functions

This study examines how modified sialic acids in mucus and erythrocytes affect influenza A virus HA and NA functions, finding that these modifications inhibit viral binding and cleavage.

Limited intra-host diversity and background evolution accompany 40 years of canine parvovirus host adaptation and spread

This study analyzes 40 years of canine parvovirus evolution, finding limited intra-host diversity and slow genetic change despite its adaptability.

Influenza Viruses in Mice: Deep Sequencing Analysis of Serial Passage and Effects of Sialic Acid Structural Variation

This study analyzes influenza A virus evolution in mice during serial passage, finding varied mutation patterns and no clear adaptive evolution or sialic acid-related sequence differences.

Expression of 9-O- and 7,9-O-acetyl modified sialic acids in cells and their effects on influenza viruses

The paper examines the expression and effects of 9-O- and 7,9-O-acetyl modified sialic acids on influenza virus infections in human and canine cells.