Synthetic STING agonists elicit powerful vaccine adjuvancy providing robust central memory and anti-tumour effects
L. D. Towner, L. N. Dahal, M. C. Taylor, K. L. Cox, T. Inzhelevskaya, M. Mack, S. R. Wedge, C. Richardson, M. S. Cragg, S. A. Beers
This study shows synthetic STING agonists enhance CD8+ T-cell responses, memory formation, and anti-tumour effects in mice, with implications for immunotherapy and vaccines.
bioRxiv · Jan 4, 2023 · PreprintImmunology