Author

L. N. Dahal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

M. S. Cragg· 2 shared A. D. Duckworth· 1 shared C. Richardson· 1 shared E. L. Saulters· 1 shared F. J. Ward· 1 shared J. F. Woolley· 1 shared J. R. Slupsky· 1 shared K. L. Cox· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

M. S. Cragg

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2 papers

Recent·Most cited

Soluble CTLA-4 raises the threshold for T-cell activation and modulates anti-tumour immunity

P. T. Kennedy, E. L. Saulters, A. D. Duckworth, Y. J. Lim, J. F. Woolley, J. R. Slupsky, M. S. Cragg, F. J. Ward, L. N. Dahal

This study shows that soluble CTLA-4 suppresses T-cell activation and promotes tumor growth in mice, and that blocking sCTLA-4 enhances anti-tumor immunity.

bioRxiv · Jun 5, 2023 · PreprintCancer Biology

Synthetic STING agonists elicit powerful vaccine adjuvancy providing robust central memory and anti-tumour effects

L. D. Towner, L. N. Dahal, M. C. Taylor, K. L. Cox, T. Inzhelevskaya, M. Mack, S. R. Wedge, C. Richardson, M. S. Cragg, S. A. Beers

This study shows synthetic STING agonists enhance CD8+ T-cell responses, memory formation, and anti-tumour effects in mice, with implications for immunotherapy and vaccines.

bioRxiv · Jan 4, 2023 · PreprintImmunology