Author

S. Raavicharla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1

Frequent Co-Authors

C. R. Knoverek· 1 shared E. Rennella· 1 shared G. R. Bowman· 1 shared L. E. Kay· 1 shared S. Singh· 1 shared T. E. Frederick· 1 shared T. Yuwen· 1 shared U. L. Mallimadugula· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

C. R. Knoverek

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1 paper

Recent·Most cited

Opening of a Cryptic Pocket in β-lactamase Increases Penicillinase Activity

C. R. Knoverek, U. L. Mallimadugula, S. Singh, E. Rennella, T. E. Frederick, T. Yuwen, S. Raavicharla, L. E. Kay, G. R. Bowman

The paper investigates how a cryptic pocket in β-lactamase, formed under the Ω-loop, enhances enzyme activity against penicillin, suggesting excited states can improve function.

bioRxiv · Apr 14, 2021Biophysics