Cells in the Polyaneuploid Cancer Cell (PACC) state have increased metastatic potential
M. M. Mallin, N. Kim, M. I. Choudhury, S. J. Lee, S. S. An, S. X. Sun, K. Konstantopoulos, K. J. Pienta, S. R. Amend
The paper identifies Polyaneuploid Cancer Cells (PACCs) as metastasis-competent cells through increased motility, elasticity, and survival in circulation.
bioRxiv · Sep 16, 2022Cancer Biology