ImmunologybioRxivPreprint
Rheumatoid arthritis patients express a skewed repertoire of polyclonal, hypomutated B-cell receptors
G. J. M. Cowan, K. Miles, L. Capitani…·M. Gray
This study identifies that RA patients have a higher proportion of poorly mutated, polyclonal IgG+ve BCRs in peripheral blood and synovium, suggesting a role in autoimmune inflammation.