Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo
G. W. Busey, M. C. Manjegowda, T. Huang, W. H. Iobst, S. S. Naphade, J. A. Kennedy, C. A. Doyle, P. V. Seegren, K. R. Lynch, B. N. Desai
This study identifies novel TRPM7 inhibitors with potent in vivo anti-inflammatory effects, showing efficacy in a mouse model of endotoxemia.
bioRxiv · May 22, 2023 · PreprintImmunology