Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
F. Sesterhenn, M. Galloux, S. S. Vollers, L. Csepregi, C. Yang, D. Descamps, J. Bonet, S. Friedensohn, P. Gainza, P. Corthesy, M. Chen, S. Rosset, M.-A. Rameix-Welti, J.-F. Eleouet, S. T. Reddy, , B. Correia
This study demonstrates that a computationally designed epitope-focused immunogen enhances subdominant neutralizing antibody responses against RSV.
bioRxiv · Nov 22, 2018Immunology