Author

S. Friedensohn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:deep learning· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:CITE-seq· 1

Frequent Co-Authors

S. T. Reddy· 5 shared L. Csepregi· 3 shared C. R. Weber· 2 shared D. M. Mason· 2 shared D. Neumeier· 2 shared F. Sesterhenn· 2 shared A. Cuny· 1 shared A. Kummer· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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5 shared papersImmunology

S. T. Reddy

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5 papers

Recent·Most cited

The Physiological Landscape and Specificity of Antibody Repertoires

L. Csepregi, K. B. Hoehn, D. Neumeier, J. M. Taft, S. Friedensohn, C. R. Weber, A. Kummer, F. Sesterhenn, B. E. Correia, S. T. Reddy

This study analyzes antibody repertoires across multiple lymphoid organs in immunized mice, finding that strong humoral responses lead to consolidated, overlapping B-cell clones and a uniform but redundant physiological landscape.

bioRxiv · Sep 15, 2021 · PreprintImmunology

Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2

R. A. Ehling, C. R. Weber, D. M. Mason, S. Friedensohn, B. Wagner, F. Bieberich, E. Kapetanovic, R. Vazquez-Lombardi, R. B. Di Roberto, K.-L. Hong, C. Wagner, D. J. Sheward, B. Murrell, A. Yermanos, A. Cuny, , S. T. Reddy

Single-cell sequencing and screening identify expanded plasma cell clones in COVID-19 patients producing SARS-CoV-2-specific neutralizing antibodies.

bioRxiv · Feb 12, 2021 · PreprintImmunology

Convergent selection in antibody repertoires is revealed by deep learning

S. Friedensohn, D. Neumeier, T. A. Khan, L. Csepregi, C. Parola, A. R. G. de Vries, L. Erlach, D. M. Mason, S. T. Reddy

This study uses deep learning to identify convergent antibody sequences in mice, showing their antigen-specificity and potential for immunodiagnostics.

bioRxiv · Feb 25, 2020 · PreprintImmunology

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

F. Sesterhenn, M. Galloux, S. S. Vollers, L. Csepregi, C. Yang, D. Descamps, J. Bonet, S. Friedensohn, P. Gainza, P. Corthesy, M. Chen, S. Rosset, M.-A. Rameix-Welti, J.-F. Eleouet, S. T. Reddy, , B. Correia

This study demonstrates that a computationally designed epitope-focused immunogen enhances subdominant neutralizing antibody responses against RSV.

bioRxiv · Nov 22, 2018Immunology

Synthetic standards combined with error and bias correction improves the accuracy and quantitative resolution of antibody repertoire sequencing in human naive and memory B cells

S. Friedensohn, J. M. Lindner, V. Cornacchione, M. Iazeolla, E. Miho, A. Zingg, S. Meng, E. Traggiai, S. T. Reddy

bioRxiv · Mar 21, 2018Immunology