Author

L. Csepregi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 6

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 5 Research Focus:cell type annotation· 4 Approach:deep learning· 3 Assay:proteomics· 3 Assay:scRNA-seq· 3 Research Focus:clustering· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2

Frequent Co-Authors

S. T. Reddy· 6 shared D. Neumeier· 4 shared S. Friedensohn· 3 shared A. Agrafiotis· 2 shared A. Oxenius· 2 shared A. Yermanos· 2 shared C. Parola· 2 shared F. Sesterhenn· 2 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

6 shared papersImmunology

S. T. Reddy

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The Physiological Landscape and Specificity of Antibody Repertoires

L. Csepregi, K. B. Hoehn, D. Neumeier, J. M. Taft, S. Friedensohn, C. R. Weber, A. Kummer, F. Sesterhenn, B. E. Correia, S. T. Reddy

This study analyzes antibody repertoires across multiple lymphoid organs in immunized mice, finding that strong humoral responses lead to consolidated, overlapping B-cell clones and a uniform but redundant physiological landscape.

bioRxiv · Sep 15, 2021 · PreprintImmunology

Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells

D. Neumeier, A. Yermanos, A. Agrafiotis, L. Csepregi, T. Chowdhury, R. A. Ehling, R. Kuhn, R. Brisset-Di Roberto, M. Di Tacchio, R. Antonialli, D. Starkie, D. J. Lightwood, A. Oxenius, S. T. Reddy

This study investigates whether clonal expansion of plasma cells is deterministic or stochastic by analyzing antigen-specificity, affinity, and epitope convergence in antibody repertoires.

bioRxiv · Jul 16, 2021Immunology

Single-cell sequencing reveals clonally expanded plasma cells during chronic viral infection produce virus-specific and cross-reactive antibodies

D. Neumeier, A. Pedrioli, A. Genovese, I. Sandu, R. Ehling, K.-L. Hong, C. Papadopoulou, A. Agrafiotis, R. Kuhn, D. Robbiani, J. Han, L. Hauri, L. Csepregi, V. Greiff, D. Merkler, , A. Yermanos

bioRxiv · Jan 29, 2021Immunology

Convergent selection in antibody repertoires is revealed by deep learning

S. Friedensohn, D. Neumeier, T. A. Khan, L. Csepregi, C. Parola, A. R. G. de Vries, L. Erlach, D. M. Mason, S. T. Reddy

This study uses deep learning to identify convergent antibody sequences in mice, showing their antigen-specificity and potential for immunodiagnostics.

bioRxiv · Feb 25, 2020 · PreprintImmunology

Molecular design, optimization and genomic integration of chimeric B cell receptors in murine B cells

T. Pesch, L. Bonati, W. Kelton, C. Parola, R. A. Ehling, L. Csepregi, D. Kitamura, S. T. Reddy

The paper designs, optimizes, and genomically integrates chimeric B cell receptors (CBCRs) in murine B cells using CRISPR-Cas9, demonstrating robust surface expression and antigen recognition.

bioRxiv · Jun 5, 2019Immunology

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

F. Sesterhenn, M. Galloux, S. S. Vollers, L. Csepregi, C. Yang, D. Descamps, J. Bonet, S. Friedensohn, P. Gainza, P. Corthesy, M. Chen, S. Rosset, M.-A. Rameix-Welti, J.-F. Eleouet, S. T. Reddy, , B. Correia

This study demonstrates that a computationally designed epitope-focused immunogen enhances subdominant neutralizing antibody responses against RSV.

bioRxiv · Nov 22, 2018Immunology