Author

S. Shirran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

M. F. White· 2 shared S. Graham· 2 shared C. Botting· 1 shared H. Chi· 1 shared J. Sleeman· 1 shared K. Morrison· 1 shared L. Gaskell-Mew· 1 shared L. Kruger· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

M. F. White

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Reversible conjugation of a CBASS nucleotide cyclase regulates immune response to phage infection

L. Kruger, L. Gaskell-Mew, S. Graham, S. Shirran, R. Hertel, M. F. White

The paper shows that the CBASS system in bacteria uses protein conjugation to regulate nucleotide cyclase activity, keeping it inactive until phage infection triggers its release.

bioRxiv · Sep 29, 2023 · PreprintMicrobiology

Antiviral Type III CRISPR signalling via conjugation of ATP and AdoMet

H. Chi, V. Hoikkala, S. Gruschow, S. Graham, S. Shirran, M. F. White

This study identifies SAM-AMP as a novel second messenger in type III-B CRISPR systems, used for antiviral signaling by conjugating ATP to S-adenosyl methionine.

bioRxiv · Jun 26, 2023 · PreprintMicrobiology

Neurochondrin interacts with the SMN protein suggesting a novel mechanism for Spinal Muscular Atrophy pathology.

L. Thompson, K. Morrison, S. Shirran, C. Botting, J. Sleeman

The paper identifies neurochondrin as an interacting partner of SMN in mobile vesicles, suggesting its role in SMA pathology and potential as a therapeutic target.

bioRxiv · Sep 1, 2017Cell Biology