S. Swaminath

Maximal interferon induction by influenza lacking NS1 is infrequent owing to requirements for replication and export

The paper investigates how genetic and phenotypic variation in influenza A virus lacking NS1 correlates with interferon production, finding that high replication and defective viral genomes are required for interferon induction despite the absence of NS1.

The rifampicin-inactivating mono-ADP-ribosyl transferase of Mycobacterium smegmatis significantly influences reactive oxygen species levels in the actively growing cells

This study shows that the M. smegmatis Arr enzyme reduces reactive oxygen species levels in actively growing cells, and its absence increases ROS, leading to higher rifampicin resistance.

Reduced Permeability to Rifampicin by Capsular Thickening as a Mechanism of Antibiotic Persistence in Mycobacterium tuberculosis

This study identifies reduced permeability to rifampicin via a thick outer layer (TOL) capsule as a mechanism for antibiotic persistence in Mycobacterium tuberculosis.