Author

S. Swanson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 2 Organism:human· 2 Assay:protein structure· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. E. Keating· 2 shared A. Savinov· 1 shared B. Duffin· 1 shared B. E. McIntosh· 1 shared B. G. Su· 1 shared C. Argus· 1 shared D. Ghose· 1 shared D. Gorkin· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

A. E. Keating

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-throughput discovery of inhibitory protein fragments with AlphaFold

A. Savinov, S. Swanson, A. E. Keating, G.-W. Li

This paper introduces FragFold, a computational method using AlphaFold to predict inhibitory protein fragments, showing high accuracy in predicting binding and inhibitory activity.

bioRxiv · Dec 19, 2023Biophysics

Discovery of diverse human BH3-only and non-native peptide binders of pro-apoptotic BAK indicate that activators and inhibitors use asimilar binding mode and are not distinguished by binding affinity or kinetics

F. Aguilar, S. Yu, R. A. Grant, S. Swanson, D. Ghose, B. G. Su, K. Sarosiek, A. E. Keating

The paper identifies new BAK binders that show similar binding modes and kinetics to both activators and inhibitors, suggesting sequence-function relationships are not determined by affinity or kinetics.

bioRxiv · May 7, 2022 · PreprintBiochemistry

Rapid changes in chromatin structure during dedifferentiation of primary hepatocytes in vitro

M. Seirup, S. Sengupta, S. Swanson, B. E. McIntosh, M. Collins, L.-F. Chu, Z. Cheng, D. Gorkin, B. Duffin, J. M. Bolin, C. Argus, R. Stewart, J. A. Thomson

This study identifies three phases of hepatocyte dedifferentiation in culture through RNA-seq and ATAC-seq, revealing rapid chromatin changes and fetal gene activation.

bioRxiv · Sep 21, 2020Cell Biology