D. Ghose

Rho and a riboswitch regulate mntP expression evading manganese stress and membrane toxicity

The paper shows Rho terminates transcription at the mntP riboswitch, and manganese activates the riboswitch to restore transcription-translation coupling, preventing membrane toxicity from overexpressed MntP.

Prioritizing landscapes to reconcile biodiversity conservation, ecosystem services, and human well-being in India

This study identifies priority landscapes in India for biodiversity conservation and ecosystem services that align with human well-being, finding that current protected areas cover only 15% of these regions.

Discovery of diverse human BH3-only and non-native peptide binders of pro-apoptotic BAK indicate that activators and inhibitors use asimilar binding mode and are not distinguished by binding affinity or kinetics

The paper identifies new BAK binders that show similar binding modes and kinetics to both activators and inhibitors, suggesting sequence-function relationships are not determined by affinity or kinetics.

Free spermidine evokes superoxide radicals that manifest toxicity

The paper shows that excess free spermidine generates superoxide radicals, causing toxicity in bacteria lacking the SpeG enzyme, while SpeG enables tolerance by neutralizing spermidine.

Kenyan Traditional Medicine: Exploring Old Solutions to the Modern Antibacterial Crises Through Natural Products Chemistry

This study evaluates the antibacterial activity of seven Kenyan medicinal plants against four bacterial species, identifying phytochemicals in active extracts.

Exploratory polarization facilitates mating partner selection in Saccharomyces cerevisiae

The paper shows yeast cells use mobile polarity sites to explore pheromone gradients, stabilizing only when they detect high pheromone levels, facilitating mating partner selection.

Escherichia coli β-clamp slows down DNA polymerase I dependent nick translation while accelerating ligation

This study shows that Escherichia coli β-clamp inhibits DNA polymerase I nick translation but promotes ligation during Okazaki fragment maturation.