Principles of dengue virus evolvability derived from genotype-fitness maps in human and mosquito cells
P. T. Dolan, S. Taguwa, M. Aguilar Rangel, A. Acevedo, R. Andino, J. Frydman
This study identifies principles of dengue virus evolvability by analyzing genotype-fitness maps in human and mosquito cells, revealing host-specific adaptation mechanisms and genetic load effects.
bioRxiv · Feb 5, 2020Microbiology