Author

P. T. Dolan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:whole-genome sequencing· 2 Organism:Arabidopsis· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Frydman· 2 shared R. Andino· 2 shared A. Acevedo· 1 shared A. B. McDermott· 1 shared C. Larabell· 1 shared D. R. Gestaut· 1 shared E. M. Sontag· 1 shared F. Morales-Polanco· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

J. Frydman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

C1q Enables Influenza HA Stem Binding Antibodies to Block Viral Attachment and Broadens the Antibody Escape Repertoire

I. Kosik, J. D. S. Santos, M. Angel, Z. Hu, J. Holly, J. S. Gibbs, T. U. Gill, M. Kosikova, T. Li, W. Bakhache, P. T. Dolan, H. Xie, S. F. Andrews, R. A. Gillespie, M. Kanekiyo, , j. yewdell

This study shows that C1q enhances anti-hemagglutinin stem antibody neutralization by blocking viral attachment and expanding the viral escape repertoire.

bioRxiv · Jun 12, 2023 · PreprintMicrobiology

An ESCRT-dependent pathway of Nuclear and Cytoplasmic Spatial PQC is coordinated at Nuclear Vacuolar Junctions

E. M. Sontag, F. Morales-Polanco, J.-H. Chen, G. McDermott, P. T. Dolan, D. R. Gestaut, M. A. LeGros, C. Larabell, J. Frydman

The paper identifies an ESCRT-dependent pathway that coordinates nuclear and cytoplasmic protein quality control (PQC) at nuclear-vacuolar junctions, enabling vacuolar clearance of misfolded proteins.

bioRxiv · Dec 1, 2022 · PreprintBiochemistry

Principles of dengue virus evolvability derived from genotype-fitness maps in human and mosquito cells

P. T. Dolan, S. Taguwa, M. Aguilar Rangel, A. Acevedo, R. Andino, J. Frydman

This study identifies principles of dengue virus evolvability by analyzing genotype-fitness maps in human and mosquito cells, revealing host-specific adaptation mechanisms and genetic load effects.

bioRxiv · Feb 5, 2020Microbiology

Antiviral adaptive immunity and tolerance in the mosquito Aedes aegyti

R. Andino, M. Tassetto, M. Kunitomi, Z. J. Whitfield, P. T. Dolan, I. Sanchez-Vargas, I. Ribiero, T. Chen, K. E. Olson

The paper characterizes an antiviral immunity pathway in mosquitoes that uses endogenous viral elements for long-term protection and self-nonself discrimination.

bioRxiv · Oct 9, 2018 · PreprintImmunology